Sergio Davinelli, Michael E. Nielsen, Giovanni Scapagnini
di Sergio Davinelli, Michael E. Nielsen, Giovanni Scapagnini
3 Maggio 2018

Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review



Abstract: Astaxanthin, a xanthophyll carotenoid, is a secondary metabolite naturally synthesized

by a number of bacteria, microalgae, and yeasts. The commercial production of this pigment has

traditionally been performed by chemical synthesis, but the microalga Haematococcus pluvialis appears

to be the most promising source for its industrial biological production. Due to its collective

diverse functions in skin biology, there is mounting evidence that astaxanthin possesses various

health benefits and important nutraceutical applications in the field of dermatology. Although still

debated, a range of potential mechanisms through which astaxanthin might exert its benefits on skin

homeostasis have been proposed, including photoprotective, antioxidant, and anti-inflammatory

effects. This review summarizes the available data on the functional role of astaxanthin in skin

physiology, outlines potential mechanisms involved in the response to astaxanthin, and highlights

the potential clinical implications associated with its consumption.


Nutrients 2018, 10, 522; doi:10.3390/nu10040522